Antimicrobials misuse in the livestock sector, aquaculture and crop production is a major concern as a risk for emergence and spread of antimicrobial resistant micro-organisms." The Food and Agriculture Organization of the United Nations
Agricultural food production is a hotspot for the dissemination of antibiotic resistance in the environment. Existing data suggests that antibiotic use in animals is as high, or in some countries even higher, as antibiotic use in humans. Antibiotic resistance can occur and develop in the gut microbiota of farmed animals and get released into the environment via animal waste. As most animal waste in agriculture is used as manure fertilizer for food production, there are concerns that antibiotic resistance may spread from Farm to Fork.learn more
COVID-19 can create a perfect storm for antibiotic-resistant infections in healthcare settings” US Centers for Disease Control and Prevention
There are two important limitations to how antibiotic resistance is currently monitored in hospitals. First, current monitoring focuses mainly on a limited number of pathogenic bacteria. Second, it is often based on passive surveillance of bacteria isolated from patients. This leads to delayed detection of outbreaks, non-comparable data, and the inability to capture other pathogenic bacteria and antibiotic resistance profiles which are often carried by commensal bacteria.
Though not a substitute for existing monitoring methods, wastewater-based monitoring can provide data that is otherwise hard to obtain and become the easiest means for obtaining comprehensive information on the prevalence of resistance in hospitals. As waste from all patients is released into wastewater, wastewater monitoring can cover a wider range of antibiotic resistance profiles compared to the partial data from a few selected pathogenic bacteria. The practical, logistical and ethical barriers to sampling wastewater are also limited.
Antibiotic resistance is an emerging water issue
Antibiotic resistant bacteria and resistance genes contained in human and animal waste are released into surface waters from wastewater treatment plants, sewage overflows, and in run-off from agricultural fields fertilised with manure. These contaminated water environments may then act as exposure routes to humans and animals, particularly if the contaminated water is used for agricultural irrigation, drinking water production, or leisure activities such as swimming. Water environments may also facilitate the emergence and the spread of resistance to different places. We support the goals of the European Green Deal and seek to protect aquatic environments.learn more
Resistomap offers a complete laboratory and analysis service to monitor antibiotic
resistance genes in any sample type.
Combining multiwell high-throughput qPCR with automated raw data-analysis and interactive visualization creates a powerful platform for antibiotic resistance gene monitoring.
384 pre-validated ARG assays
SmartChip™ qPCR technology.
Quantification relative to 16S rRNA gene. Interactive heatmap for ARG levels. Custom Analysis as service.
Sample collection advice and service.
DNA extraction from any sample
We assist and give consultation on sampling best practices, (e.g. selecting the right DNA extraction kits), experimental design, and
routine monitoring planning.
We recommend to shipping the samples using international courier service with tracking number.
SmartChip is a configurable multiwell real-time PCR platform. We have configured the SmartChip platform to fit your needs and samples: Exploratory screening with 384 genes, followed with customizable subset for focusing or monitoring most important hits, or for comprehensive profiling all 384 genes.
Quantification of ARGs relative to 16S rRNA, presented in an interactive heatmap. Interpretation of results and custom figures are also available upon request.
Flexibility of the SmartChip™ platform allows for high gene-content screening and high-throughput monitoring configurations
Prices exclude 24% VAT
Prices exclude 24% VAT