Resistomap platform

Water biosecurity platform

Biosecurity intelligence

The complete package for routine surveillance of AMR in WWTPs

Resistomap offers a comprehensive solution designed specifically for wastewater treatment plants to easily integrate routine monitoring of antibiotic resistance into your daily operations. Our service combines cutting-edge gene analysis with the powerful Resistomap Platform, enabling you to track and manage antimicrobial resistance (AMR) levels effectively.

Our service is designed together with water professionals to be a useful addition to existing operations, making it easy to implement and maintain routine surveillance of AMR & antibiotic resistance. With Resistomap, you can ensure that your plant is effectively managing AMR risks, contributing to public health, and meeting regulatory requirements.

96 genes

Comprehensive, targeted gene quantification designed for routine AMR monitoring in water and wastewater.

5 days

Analysis results available within approx. five business days from sample's arrival at our laboratory.

Use cases

Health sentinel
✓
Complement patient data with population level insights
✓
Early warning system from population angle
Enhance antibiotic stewardship
‍
✓
Pollution tracking
✓
Track hotspots of AMR pollution
sources efectively
✓
Enhance antibiotic stewardship
Early warning system from population angle
‍
✓
Process performance
✓
Evaluate process and treatment technology efficiency
✓
Identify improvement opportunities
Solution development to reduce
AMR burden
✓
Designed together with wastewater treatment and water utility professionals.
Do you want to discuss how our water biosecurity platform can be implemented and used within your operational procedures and fit the internal systems, contact us through our form and select WWTP consultation.
Request consultationSee demo

Service steps

How we start:
AMR Monitoring Design
By providing customised antibiotic resistance monitoring solutions and comprehensive onboarding support, we cater to the unique requirements of each client. We thoughtfully consider all relevant factors, from sampling accessibility to existing protocols and system integration, to deliver a tailored approach that addresses your specific needs.
What we test:
Water and Wastewater Sample Analysis
Our water biosecurity platform welcomes all types of client water and wastewater samples, offering comprehensive services that cater to your needs:
‍
  • Installation of automated composite water samplers, when needed.
    ‍
  • Detailed water sampling protocols.
    ‍
  • Sampling kits equipped with 0.22 µm pore-sized PES filter units for effective water sample filtration.
    ‍
  • Global pick-up and temperature-controlled transportation services to securely deliver your samples to our laboratory facilities.
We also accept extracted eDNA if your operations include in-house DNA extraction, ensuring a seamless analysis process.
How we measure:
High-throughput qPCR system
We utilise advanced molecular technology to detect and quantify AMR genes. Our laboratory process includes:
‍
  • Environmental DNA (eDNA) extraction using commercial DNA extraction kits optimised for the isolation of bacterial DNA from water samples.
    ‍
  • All extracted DNA is quality-controlled to ensure standardised and precise analysis.
    ‍
  • High-throughput gene quantification using the SmartChip qPCR system by Takara Bio, targeting the 96 pre-defined gene markers.
How we deliver results:
Resistomap platform
Our cloud-based Resistomap Platform processes the quantitative AMR data and transforms it into clear, actionable insights, giving clients comprehensive information on AMR levels over time and across geographical locations.

Our analyses generate key metrics, such as:
‍
  • Antibiotic Resistance Gene Index (ARGI):
    A comparable metric for assessing environmental antibiotic resistance gene abundance, derived from the mean relative abundance of a standardised set of highly relevant ARGs.
    ‍
  • AMR Gene Removal
    A tool to evaluate the efficiency of processes and technologies in reducing AMR pollution, based on the percentage of AMR gene copies removal.
    ‍
  • AMR Comparative Risk Score
    ‍    A feature enabling users to assess and compare AMR risks across different processes and environments, based on quantified AMR gene levels, pathogens, mobile genetic elements and genes associated with environmental pollution markers in water samples. 
What we measure:
96-Genes Panel for One Health
Drawing from our extensive internal database on environmental antimicrobial resistance genes, which has been cultivated over six years of service and research, we have identified 96 key genes for routine monitoring in water environments. The curated 96-gene panel consist of:

61 Antibiotic Resistance Genes (ARGs)
‍
  • Aminoglycoside
  • Beta Lactam (incl. Carbapenem & Cephalosporin)
  • Multi-Drug Resistance
  • Macrolide-Lincosamide-Streptogramin B
  • Phenicol
  • Quinolone
  • Sulfonamide
  • Tetracycline
  • Vancomycin
14 Pathogens
ESKAPE 
  • Enterococci
  • S. aureus & Staphylococci
  • K. pneumoniae
  • A. baumannii
  • P. aeruginosa
Water Safety 
  • E. coli
  • S. typhi
  • V. cholerae
  • Shigella
  • Legionella
  • Campylobacter
Fungal
  • C. auris
  • C. albicans
in addition to
  • 10 Mobile Genetic Elements (MGEs) - Class 1 Integron, plasmids, insertion sequences, transposons.
  • 6 Environmental Pollution Markers - CrAssphage, Mercury, Biocide, Colistin resistance.
  • 4 Microbial Source Tracking (MST) - Human, Bovine, and Swine.
  • 1 Bacterial DNA Control - 16S rRNA Gene.

In total, Resistomap's comprehensive gene detection and quantification capabilities encompass a total set of 620 genes.
‍

Are you working in LMICs?

Contact us to find out how we can support

Contact usCountries lists

Monitor antibiotic resistance with our cutting-edge technology

Contact us to see how our biosecurity intelligence platform can benefit your organization

Contact usABout